Therapeutic benefits from a poorly absorbed prednisolone enema in distal colitis.
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منابع مشابه
Therapeutic benefits from a poorly absorbed prednisolone enema in distal colitis.
A double blind controlled trial has been conducted in 40 patients to compare the therapeutic effects of prednisolone metasulphobenzoate enemas with those of prednisolone-21-phosphate enemas. Both enemas brought about improvement in symptoms and sigmoidoscopic appearances in more than 70% of patients treated. The absorption of prednisolone from the metasulphobenzoate enema in three patients was ...
متن کاملPlasma prednisolone levels and adrenocortical responsiveness after administration of prednisolone-21-phosphate as a retention enema.
Plasma prednisolone levels have been measured by radioimmunoassay after oral and rectal administration to healthy volunteers and to patients with idiopathic proctocolitis. The amount of prednisolone absorbed from a 20 mg retention enema given to patients with proctocolitis was about 44% of that absorbed from the same dose orally administered. Adrenocortical response to synthetic ACTH in patient...
متن کاملCaustic colitis due to formalin enema.
Colitis has been reported by rectal instillation of a variety of agents: soap enemas, water-soluble contrast media, hydrogen peroxide, vinegar, potassium dichromate, potassium permanganate, copper sulfate, brown sugar, glutaraldehyde, non-steroidal anti-inflammatory agents, and ethyl alcohol. We report a 54-year-old man, who accidentally received a 100-ml enema of 10% formalin. Within minutes t...
متن کاملComparative study of enema retention and preference in ulcerative colitis.
BACKGROUND Therapeutic enemas are often used to treat active colitis but their retention may be limited because of urgency to defecate. Some preparations may be better retained and tolerated than others because of their physical properties. AIM To compare patient preference and retention of four therapeutic enemas, including a nicotine enema, in patients with ulcerative colitis (UC). METHOD...
متن کاملdistal ulcerative colitis
Accepted for publication 24 August 1995 Abstract Distal ulcerative colitis can be treated with oral or rectal mesalazine, or both. A foam enema preparation has been developed and its efficacy investigated. The aim of this study was to evaluate the efficacy and safety of mesalazine foam enemas compared with prednisolone foam enemas in the treatment of patients with acute distal ulcerative coliti...
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ژورنال
عنوان ژورنال: Gut
سال: 1985
ISSN: 0017-5749
DOI: 10.1136/gut.26.8.822